6 empirical effects (benefits) of Cordyceps Sinensis on your body

Cordyceps is a widely used Chinese medicine with a history of more than 700 years

It is generally believed that in addition to its anti-cancer, anti-oxidant, anti-inflammatory, and anti-microbial effects, its products also have clinical health care effects on the liver, kidney, cardiovascular, respiratory, nervous, and immune systems.

In recent years, due to its extensive clinical and commercial value, wild Cordyceps has the highest price at about US$20,000 to US$40,000 per kilogram. It is called "soft gold" or "Himalayan Viagra" in China.

In empirical medicine, what are the effects of Cordyceps sinensis? 

Are there any side effects or contraindications? 


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1. Cordyceps is good for arrhythmia

Cardiac arrhythmia (Cardiac arrhythmia) refers to a group of conditions that cause the heart to beat irregularly, too slowly, or too fast. In this case, a person's heart may be beating too slow (60 beats/minute), too fast (100 beats/minute), too early, or irregular rhythms.

Symptoms of arrhythmia are dizziness, palpitations, fast heartbeat, feeling weak, shortness of breath, chest pain, and extra strong heartbeat.

About 50% of heart disease patients die from arrhythmia, but it can be controlled by an automatic external defibrillator. If used quickly within a few minutes after the first heart attack, it can reduce mortality.

A systematic literature review and integrated analysis (Meta-analysis, including 13 randomized controlled trials, with a total of 1379 arrhythmia patients) pointed out that compared with the control group that only used antiarrhythmic western medicine,  (Cordyceps sinensis) Mycelium) combined with anti-arrhythmic western medicine for intervention, is better than the control group in terms of clinical efficacy, dynamic electrocardiogram, and average heart rate in patients with bradycardia. There is statistical significance .

In addition, Cordyceps Sinesis have fewer adverse reactions and may reduce the side effects of antiarrhythmic drugs.

*Conclusion: For cardiac arrhythmia,  (Cordyceps sinensis mycelium) may bring positive help, but it is limited due to the limited quality of the included studies, and more studies are needed to support it.


2. Cordyceps is good for chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease is characterized by progressive and persistent airflow obstruction, accompanied by increased chronic inflammatory response, mainly caused by environmental exposure to smoke and smoking, and is one of the top ten causes of death in the world

Relevant clinical manifestations include dyspnea, chronic cough, low exercise capacity, audible wheezing, and more frequent or longer-lasting bronchial infections, which can cause weight loss in severe cases.

Cordyceps preparations or formulas containing Cordyceps have effects on lung function and exercise.There are potential benefits for endurance, quality of life, and improvement in symptoms .

*Conclusion: For chronic obstructive pulmonary disease, Cordyceps sinensis may be able to help, but due to the small sample size and publication bias, more studies are needed for further verification


3. Cordyceps is good for chronic kidney disease

Chronic kidney disease is a common disease that refers to the long-term loss of kidney function. It is often diagnosed with other comorbidities (especially hypertension, diabetes, and cardiovascular disease)

For most patients with chronic kidney disease, the risk of cardiovascular events is greater than the risk of developing end-stage renal disease. In the global burden of disease study, it is the 18th most common cause of death

A Cochrane Database of Systematic Reviews (Cochrane Database of Systematic Reviews, including 22 randomized controlled studies, with a total of 1746 patients who did not receive dialysis for chronic kidney disease) pointed out that Cordyceps preparations, as an adjuvant treatment of conventional drugs, showed a decrease in serum creatinine and an increase in serum creatinine. Creatinine clearance rate, reduction of proteinuria and alleviation of chronic kidney disease-related complications (such as increasing hemoglobin and serum albumin) .

*Conclusion: For chronic kidney disease, oral cordyceps-related preparations may be positively helpful to the condition, but due to the low quality of existing evidence, more studies are needed for further verification


4. Cordyceps is good for kidney transplantation

Since Joseph Murray performed the first kidney transplantation in 1954, kidney transplantation has been regarded as the most economical and effective treatment for end-stage kidney disease.

Complications of kidney transplantation can be divided into pathology and surgery. Pathological complications include rejection, infection, and cardiovascular events, while surgical complications include vascular and urinary system complications, lymphangioma, wound infection, and hernia.

A systematic literature review and integrated analysis (Meta-Analysis, including 9 randomized controlled trials, a total of 907 kidney transplant patients) pointed out that the combined use of cordyceps preparations can help reduce hyperuricemia, The incidence of hyperlipidemia, hyperglycemia, proteinuria and liver damage, and reduce the nephrotoxicity caused by treatment . 

*Conclusion: Cordyceps sinensis may be beneficial to kidney transplant patients as an adjuvant treatment of conventional immunosuppressive agents. However, due to the low-quality problems of existing evidence, more high-quality large-scale studies are still needed for further verification


5. Cordyceps is beneficial for immune regulation

The immune response plays a vital role in maintaining human health by identifying and killing pathogens, senescent cells or tumor cells

Immune regulation refers to the ability of the immune system to control various life-threatening diseases, such as cancer, human immunodeficiency virus, multiple sclerosis and aging.

A randomized, double-blind, placebo-controlled clinical trial (8-week period and 80 healthy adults) pointed out that oral cordyceps mycelium extract can increase the activity of natural killer cells. 

*Conclusion: Cordyceps may have immunomodulatory effects, but due to the small number of samples, more studies are needed to support it.


6. Cordyceps is good for chronic hepatitis B

An estimated 400 million people worldwide are infected with chronic hepatitis B virus (hepatitis B virus), causing approximately 750,000 deaths each year from related complications

Carriers of hepatitis B virus are not only prone to cirrhosis and liver insufficiency, but the risk of hepatocellular carcinoma is increased by 100 times.

Therefore, early diagnosis and treatment are essential to reduce the morbidity and mortality of chronic hepatitis B infection.

A randomized controlled trial (6 months for 60 patients with chronic hepatitis B) pointed out that oral Xinanbao capsules (composition of artificial cordyceps mycelium powder) can reduce serum ALT, AST, hyaluronic acid, Type Ⅲ procollagen and Laminin levels . 

*Conclusion: For hepatitis B, Cordyceps may bring positive help, but due to the small sample size, more studies are needed for further verification.